Amino Acid Substitutions Conferring Reduced Sensitivity to Selected Protease Inhibitors
| saquinavir (Invirase) | 48 | 90 | ||||||
| ritonavir (Norvir) | 36 | 46 | 54 | 71 | 82 | 84 | ||
| indinavir (Crixivan) | 36 | 46 | 54 | 71 | 82 | 84 | 90 | |
| nelfinavir (Viracept) | 48 | 84 | 90 | |||||
| VX-478 | 46 | 84 |
Amino Acid Substitutions Conferring Reduced Sensitivity to Selected Protease Inhibitors
| saquinavir (Invirase) | 48 | 90 | ||||||
| ritonavir (Norvir) | 36 | 46 | 54 | 71 | 82 | 84 | ||
| indinavir (Crixivan) | 36 | 46 | 54 | 71 | 82 | 84 | 90 | |
| nelfinavir (Viracept) | 48 | 84 | 90 | |||||
| VX-478 | 46 | 84 |