In 2017, Treatment Action Group and partners introduced the “fair share” funding targets for TB research. The fair share targets called for each country to spend at least 0.1% of its overall R&D expenditures on TB R&D in order to meet global TB research funding goals set by Stop TB Partnership and endorsed by United Nations member states. Six years on, it is time to refresh the fair share targets to reflect current TB research funding needs and changes in country R&D capacity and spending. This TAG Information Note provides detail on the new 0.15% fair share targets and the methodology and sources of data behind them. Structured as a series of 12 questions/answers, this document is intended to be used as reference by advocacy partners and can be cited by partners when using the fair share targets to raise global and national funding for TB R&D.