More Mixes Nixed By Concentration Preoccupations By Yasmin Halima and Rob Camp Statin Strength Relative Potency of the HMG-CoA Reductase Inhibitors (a.k.a. Statins) Drug Daily Dose Relative Potency* Fluvastatin (Lescol) 60 mg 1 Pravastatin (Pravachol) 60 mg 2 Lovastatin (Mevacor) 20 mg 3…
French Researchers Question Benefit of Lifelong Antiretroviral Treatment The following are excerpts from "Effect of highly active antiretroviral therapy over 5 years," Jean-Pierre Viard and colleagues (Service d'Immunologie Clinique, Centre Hospitalier Universitaire Necker-Enfants Malades, Paris). It is more and more…
Treatment Advocates Strategize At TAG's 2nd Annual International TB/HIV Workshop Activists From 31 Countries Building on the success of the First International TB/HIV Community Education and Mobilization Workshop, held in conjunction with the 33rd International Union Against Tuberculosis and Lung…
Merck Vaccine Moves Forward With Efficacy Trial, While Special Committee Tries to Salvage Thai Study "Going for Broke in Bangkok" At the recent meeting of the NIH's AIDS Vaccine Research Working Group (May 27-28, 2004), there were discussions of two…
French African Study Offers Critical Challenge to Generics Obstructionists By Mike Barr Railing Against Randall Tobias As if there were ever any legitimate doubt, it is now official: the three-in-one generic HAART pill ("Triomune," manufactured in India by the huge…
Pfizer Working Session in Bangkok---Invitation to Richard Stern and Dr. Stern's reply 15 June 2004 Ann Prochilo Pfizer and Company San Francisco, California Dear Ann: Thanks for this invitation [posted below this response] to participate in a forum in Bangkok…
Quirky PK of BI's Tipranavir May Confine Its Use to Limited Rescue Role By Rob Camp Penned in by PK Advances in HIV pharmacology can theoretically lead to improvements in HIV care. The monitoring of antiretroviral drugs including virologic, immunologic…
Abbott, Trimeris/Roche Pricing Decisions Rekindle Old R&D Cost Questions Drug R&D Estimate (Millions) Source Invirase <$100 Interviews Norvir <$100 J. Leonard Crixivan $312* Internal memos Viracept $150 SEC docs. Agenerase <$200 SEC docs. * Goozner's estimate of Merck's total investment…
Little-Noticed Ban of Little-Used Drug Triggers Little-Known Investigation By Dr. Paul C. Bellman Whither the Checks and Balances? On April 9th, a New York City treating physician, Dr. Paul C. Bellman, submitted a treatise-length letter of protest to members of…
Vicissitudes of Medicine and Marketing Take Toll on Me-Too Line Up By Rob Camp B-I the New Salvage Outfit? Pipelines are almost as delicate and fragile as the ecosystems they go trampling through, writes TAG's Antiviral Project Director Rob Camp…