Activist Epistler Chronicles Frightening Tales of Multiply Resistant HIV from D.C. Principles Panel Toxic cocktail The NIH panel convened late last November to develop new state-of-the-art guidelines for the treatment of HIV infection included a series of provocative (some would…
Dutch Research Team Challenges Ho/Shaw Pathogenetic HIV Model and Gives Cause for Pause Telomeres' fifteeen minutes As long ago as 1995, when the back-to-back Ho and Shaw viral dynamics papers were published, HIV disease has been likened to a colossal…
Resistance and cross-resistance among protease inhibitors Resistant to: Cross-resistance profile SQV 10/12 patients with L90M + 48 had complete or partial loss of sensitivity to other protease inhibitors. RTV Most or all RTV-resistant isolates are resistant to IDV and NFV.…
Four in Favor, Four Against; Long-Awaited Non-Nuke Receives Mixed Reviews at Agency Hearing Clinical benefit elusive In a November 22nd FDA hearing that harkened back to the bad old days of ddC, the Food and Drug Administration's Antiviral Drugs Advisory…
At NIH-Sponsored 'Principles' Panel, A First Peek at Second Phase Decay Data -- and at Lymphoid Architecture FDCs as storage depots In mid-November, an NIH panel convened under the auspices of the Office of AIDS Research (OAR) to discuss scientific…
"It's the Faucet, Stupid." Comparing something called telomere lengths of CD4+ and CD8+ T lymphocytes in HIV-infected and uninfected persons, Amsterdam's Frank Miedema et al. claim "there is no evidence for increased turnover of CD4+ T cells in HIV infection."…
Devastating Funding Proposal Undermines the Global Fight Against AIDS by Coco Jervis A sense of disbelief washed over the global AIDS community last month when President Obama unveiled his fiscal year 2013 budget proposal to cut $563 million from the…
Merck’s Cavalier Attitude Toward the Welfare of HIV/HCV-Coinfected Patients by Tracy Swan In places where access to antiretroviral therapy is widespread, people living with HIV are now dying from a common and curable coinfection: hepatitis C virus (HCV). HIV increases…
by Richard Jefferys In the earliest days after the discovery of HIV in the mid-1980s, uncertainty reigned regarding how the immune system responded to the virus. Initially, it was thought that the time between HIV infection and the development of…
