Research Toward a Cure Trials
A listing of clinical trials and observational studies related to the research effort to cure HIV infection, mainly derived from the clinicaltrials.gov online registry.
TB Representative Studies Rubric (TB RSR)
TAG and the Community Research Advisors Group (CRAG) are happy to introduce the TB Representative Studies Rubric (TB RSR), a new tool that community advisory boards (CABs) can use when designing and reviewing clinical trials protocols. The TB RSR is a 17-item questionnaire that assesses whether TB treatment trials include the types of people who get TB.
Story: HIV cure “breakthrough” with mRNA-delivered Tat protein
June 2025 Media coverage: Breakthrough in search for HIV cure leaves researchers ‘overwhelmed’ - Kat Lay, The Guardian, June 5, 2025 Major breakthrough in battle for HIV cure ‘previously thought impossible’ - Athena Stavrou, Independent, June 5, 2025 Used in…
HIV Cure Research Information Sheet
Research into curing HIV infection is ever-changing as new discoveries are made and scientists report additional rare — but informative — cases of individuals likely cured of HIV.
Story: HIV “completely eliminated” from cells in a laboratory dish with CRISPR technology
March 2024 Media coverage: Scientists say they can cut HIV out of cells - Michelle Roberts, BBC, March 20, 2024 HIV cure breakthrough as virus eliminated from cells in laboratory - Nina Massey, The Independent, March 20, 2024 Hopes of…
Washington D.C. Community Consensus on the Earlier Inclusion of Pregnant Women and Persons in TB Research
In October 2023, sixteen members of the global TB community developed a consensus statement on the inclusion of pregnant and breastfeeding women and persons in TB treatment and vaccines research.
Story: CRISPR-Based Cure for HIV “could be months away”
October/November 2023 Media coverage: CRISPR gene therapy appears safe, but claims of an imminent HIV cure are premature - Liz Highleyman, AIDSMap, November 3, 2023 Cure for HIV could be months away as first three patients are injected with new…
Treatment Action Group Resource on the Demographics of Participation in HIV Cure-Related Clinical Research
In 2014, TAG began tracking HIV cure-related trials and observational studies and making the information available as a listing on our website. The primary sources are online study registries, particularly the US-based clinicaltrials.gov.
An Activist’s Protocol Review Toolkit
An Activist’s Protocol Review Toolkit is designed to facilitate community participation in the development and review of clinical trials protocols.
CROI 2023 Tuberculosis Research Round Up
Treatment Action Group (TAG) welcomes the tuberculosis (TB) data presented at the 2023 Conference on Retroviruses and Opportunistic Infections (CROI).